Publications

Bulk RNA-seq Dataset

Chen, D., Liu, W., Zimmerman, J., Pastor, W. A., Kim, R., Hosohama, L., Ho, J., Aslanyan, M., Gell, J. J., Jacobsen, S. E., & Clark, A. T. (2018). The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell reports, 25(13), 3591–3602.e5. https://doi.org/10.1016/j.celrep.2018.12.011

Chen, D., Liu, W., Lukianchikov, A., Hancock, G., Zimmerman, J., Lowe, M., Kim, R., Galic, Z., Irie, N., Surani, MA., Jacobsen, SE., Clark, AT (2017). Germline competency of human embryonic stem cells depends on eomesodermin.  Biology of Reproduction 97:850-861

Single Cell RNA-seq Dataset

Chen, D., Sun, N., Hou, L., Kim, R., Faith, J., Aslanyan, M., Tao, Y., Zheng, Y., Fu, J., Liu, W., Kellis, M., & Clark, A. (2019). Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. Cell reports, 29(13), 4568–4582.e5. https://doi.org/10.1016/j.celrep.2019.11.083

TE Analysis of human germline

Xiang, X., Tao, Y., DiRusso, J., Hsu, F. M., Zhang, J., Xue, Z., Pontis, J., Trono, D., Liu, W., & Clark, A. T. (2022). Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections. Nature communications, 13(1), 463. https://doi.org/10.1038/s41467-022-28105-1