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Lab W |

Lab W fullpage
life decoders

Explore the World & Adventure in Science


ABOUT US

Who Are We

We are a group of scientists from 🏫 ZJU-UoE Institute working on decoding puzzles in bio-medical sciences. Topics we are interested in include epigenetic regulation of transposable elements in stem cells and cancer, genomics technology and bioinformatic algorithm development.
By combining both "wet lab" (experimental 🔬) and "dry lab" (computational 💻) approaches, we hope to provide our unique expertises in advancing our understandings for bio-medical sciences.

我们是一群来自浙江大学爱丁堡大学联合学院 🏫的生物医学方向的科学家。我们研究的内容包括干细胞细胞命运决定中的 表观遗传调控机制 基因组学大数据挖掘以及 生物信息算法及工具 的开发。我们实验室由一群来自生物学、临床医学、基础医学、生物医学以及生物信息学不同学科背景的博士后、研究生、科研助理及本科生组成。通过”干实验“(计算相关 💻)以及”湿实验“(实验技术 🔬)相结合的手段,我们希望以我们独特的视角来研究生物医学中重要的科学问题。

RESEARCH

We Are Exploring

Item 1

Biomedical science UNMASKING CELL PLURIPOTENCY

  1. Epigenetic regulation of cell fate determination in human embryonic stem cells and mesenchymal stem cells
  2. Epigenetic mechanisms of retrotransposon silencing in mammalian systems

Item 1

Bioinformatics DATA-DRIVEN BIOMEDICINE

  1. Development of bioinformatics algorithms and databases for epigenetic multiomics and single-cell omics data
  2. Development of computational Immunology Algorithm based on deep learning

MEMBERS

Meet Our Team

Wanlu Liu

Wanlu Liu, Ph.D. Principal Investigator

Assistant Professor, ZJU-UoE institute, Zhejiang University

📧 wanluliu@intl.zju.edu.cn 👩🏻‍💻 Personal Homepage @ ZJU
Siqian jin

Siqian Jin Lab Manager

M.S., Clinal Medicine (Ophthalmology), Wenzhou Medical University

📧 siqianjin@intl.zju.edu.cn
Junxun Lin

Junxin Lin, Ph.D. postdoctoral researcher

Ph.D. in Stem cell and regenerative medicine, Zhejiang University

📧 linjunxin@zju.edu.cn
Yixin Guo

Yixin Guo Ph.D. Student,Co-mentored with Dr.Wang Lie

B.Eng., Bioinformatics, Southwest JiaoTong University

📧 yixinguo@zju.edu.cn
Dengfeng Ruan

Dengfeng Ruan Ph.D. STUDENT, CO-MENTORED WITH DR.SHEN WEILIANG

M.S., Clinical Medicine (Surgery), Zhejiang University

📧 dfruan@zju.edu.com
Xinyu Xiang

Xinyu Xiang Ph.D. Student

B.S., Applied Bioscience, Zhejiang University

📧 xxyxiangxinyu@163.com
Bing Gao

Bing Gao Master Student

B.Eng.,Bioengineering, Beijing University of Chemical Technology

📧 971223798@qq.com
Lize Wu

Lize Wu Ph.D. Student

Major in Biomedical science, ZJU-UoE Institute, Zhejiang University

📧 lize.17@intl.zju.edu.cn
Xinyi Chen

Xinyi Chen Master Student

Major in Horticulture, Zhejiang University

📧3170100513@zju.edu.cn
Ruonan Tian

Ruonan Tian Master Student

Major in Bioinformatics, Huazhong Agricultural University

📧 ruonan.21@intl.zju.edu.cn
Yiwen Xu

Yiwen Xu Master Student

Major in Clinical medicine, Nanjing Medical University

📧 22118103@zju.edu.cn
Jiaxin Wu

Jiaxin Wu Master Student

Major in Biotechnology , Yunnan University

📧 jiaxin2.22@intl.zju.edu.can
Yaqi Su

Yaqi Su Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 yaqi.19@intl.zju.edu.cn
Ruihong Yuan

Ruihong Yuan Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 ruihong.19@intl.zju.edu.cn
Zhejian Yu

Zhejian Yu Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 Zhejian.19@intl.zju.edu.cn
Xinyue Huang

Xinyue Huang Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 xinyue.20@intl.zju.edu.cn
Xinyue Huang

Shiyao Li Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 shiyao.19@intl.zju.edu.cn
Xinyue Huang

Meiting Gong Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 meiting.19@intl.zju.edu.cn
Cat

Meet Our Cats

sql

juno

Host: Wanlu Liu

sql

Sql

Host: Wanlu Liu

Cola

Cola

Host: Junxin lin

tutu

Tutu

Host: Junxin lin

Kiki

Kiki

Host: Xinyu Xiang

lark

Lark

Host: Lize Wu

Qiuqiu

Qiuqiu

Host: Ruonan Tian

mibu

Mibu

Host: Siqian Jin

littleeggette

Miss Mei

Host: Siqian Jin

ALUMNI

Previous Students

Kaiwen Luo

Kaiwen Luo current Ph.D. Student at Caltech

📧 kluo@caltech.edu
Ziyuan Han

Ziyuan Han Current Ph.D. Student in UCSD

B.S., Biomedical Science, Zhejiang University
B.S., Biomedical Science, University of Edinburgh

📧z2han@ucsd.edu
Shiqi Xu

Shiqi Xu Undergraduate Researcher

Major in Biomedical Sciences, ZJU-UoE Institute, Zhejiang Univeristy

📧 shiqix.18@intl.zju.edu.cn
Adele Valeria

Adele Valeria Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang Univeristy

📧 Valeria.18@intl.zju.edu.cn
Hanqi Xie

Hanqi Xie Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang Univeristy

📧 Hanqi.18@intl.zju.edu.cn
Yanran Qiu

Yanran Qiu Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang Univeristy

📧 yanran.18@intl.zju.edu.cn
Chook Hou Wei

Chook Hou Wei Undergraduate Researcher

Major in Biomedical Science, ZJU-UoE Institute, Zhejiang University

📧 houwei.18@intl.zju.edu.cn
Jingkai Chen

Jingkai Chen Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 jingkai.19@intl.zju.edu.cn
Weijian Wang

Weijian Wang Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 weijian.19@intl.zju.edu.cn
Pengshan Li

Pengshan Li Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute,Zhejiang University

📧 pengshan.19@intl.zju.edu.cn
Lingyuan Ye

Lingyuan Ye Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 lingyuan.19@intl.zju.edu.cn
Lanqi Wu

Lanqi Wu Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang Univeristy

📧 lanqi.18@intl.zju.edu.cn
jiayi Shen

Jiayi Shen Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang Univeristy

📧 jiayi.18@intl.zju.edu.cn
Yiwei Zhang

Yiwei Zhang Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 yiweiz.18@intl.zju.edu.cn
Zhiheng Jia

Zhiheng Jia Undergraduate Researcher

Major in Biomedical Science, ZJU-UoE Institute, Zhejiang University

📧 zhihengjia.17@intl.zju.edu.cn
Ge Lu

Ge Lu Undergraduate Researcher

Major in Biomedical Science, ZJU-UoE Institute, Zhejiang University

📧 ge.17@intl.zju.edu.cn
Yuxing Zhou

Yuxing Zhou Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 yixing.18@intl.zju.edu.cn
Zhikai Xu

Zhikai Xu Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 zhikai.18@intl.zju.edu.cn
Jingrui Lu

Jingrui Lu Undergraduate Researcher

Major in Bioinformatics, ZJU-UoE Institute, Zhejiang University

📧 jingrui.20@intl.zju.edu.cn
Jinchun Zhang

Jinchun Zhang Undergraduate Researcher

Major in Biomedical Science, ZJU-UoE Institute, Zhejiang University

📧 jinchun.18@intl.zju.edu.cn
PUBLICATIONS

Our Works

*co-first author, #Corresponding author, members of our group are underlined.

2022

38. Ai, Z.*, Xiang, X.* , Xiang, Y.*, Szczerbinska, I.*, Qian, Y.*, Xu, X., Ma, C., Su, Y. , Gao, B. , Shen, H., Ramli, M., Chen, D., Liu, Y., Hao, J., Ng, H., Zhang, D. #, Chan, Y. #, Liu, W.# , Liang, H.# 2022. Kruppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency. Cell Reports , 40, 111240. link
37. Wang, L.*, You, X.*, Ruan, D.* , Shao, R., Dai, H., Shen, W., Xu, G., Liu, W.# , Zou, W. # 2022. TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes. Nature communications. Nature Communications , 13, 4709. link
36. Xiang,X.* , Tao,Y., DiRusso,J., Hsu, F.M., Zhang, J. , Xue, Z. , Pontis,J., Trono,D., Liu, W.# , Clark,A. #, 2022. Human reproduction is regulated by retrotransposons derived from ancient Hominidae-specific viral infections, Nature Communications , 13, 463. link
35. Lin, J.* , Yang,Y., Zhou, W., Dai, C. , Chen,X., Xie,Y., Han,S., Liu,H., Hu,Y., Tang,C., Bunpetch,V., Zhang,D., Chen,Y., Zou,X., Chen,D., Liu, W.# , Ouyang,H. #, 2022. Single cell analysis reveals inhibition of angiogenesis attenuates the progression of heterotopic ossification in Mkx−/− mice, Bone research , 10, 4. link

2021

34. Ruan,D.* , Tang,C.*, Fei,Y*, Qian,S., Xiang,X. ,Xu,J., Huang,Z., Chen,X., Heng,B., Yin,Z., Chen,W., Liu, W. , Shen,W.#, Ouyang,H.#; 2021. Early-Stage Primary Anti-inflammatory Therapy Enhances the Regenerative Efficacy of Platelet-Rich Plasma in a Rabbit Achilles Tendinopathy Model, The American journal of sports medicine , 49(12): 3357-3371. link
33. Wu, L.* , Xue, Z.* , Jin, S. , Zhang, J. , Guo, Y. , Bai, Y., Jin, X., Wang, C., Wang, L., Liu, Z., Wang, J.Q., Lu, L.#, Liu, W.# , 2021. huARdb: human Antigen Receptor database for interactive clonotype-transcriptome analysis at the single-cell level, Nucleic Acids Research , gkab867. link
32. Jin, S.* , Xue, Z.* , Zhang, J. , Wang, Z., Zhang, J., Chen, D.#, Liu, W.# , Lin, J.# , 2021. Identification of SRSF3 target mRNAs using inducible TRIBE. Biochemical and Biophysical Research Communications. link
31. Hancock GV, Liu, W. , Peretz,L, Chen,D, Gell,J., Collier,AJ, Zamudio,JR, Plath,K, Clark,AT.#, 2021. Divergent roles for KLF4 and TFCP2L1 in naive ground state pluripotency and human primordial germ cell development. Stem Cell Res 55:102493. link
30. Liu, W. *# , J. Gallego-Bartolomé*, Y. Zhou , Z. Zhong, M. Wang, S. P. Wongpalee, J. Gardiner, S. Feng, P. H. Kuo and S. E. Jacobsen.#, 2021. Ectopic targeting of CG DNA methylation in Arabidopsis with the bacterial SssI methyltransferase. Nature Communications 12(1): 3130. link
29. Guo, Y. , Xue, Z. , Yuan, R. , Li, J., Pastor, W. & Liu, W.# , 2021. RAD: a web application to identify region associated differentially expressed genes. Bioinformatics , btab075. link
28. Zhong, Z., Feng, S., Duttke, S.H., Potok, M.E., Zhang, Y. , Gallego-Bartolomé, J., Liu, W.# & Jacobsen, S.E.#, 2021. DNA methylation-linked chromatin accessibility affects genomic architecture in Arabidopsis. Proceedings of the National Academy of Sciences . 118(5), e2023347118. link

2020

27. Yuan, C.*, Pan, Z.*, Zhao, K.*, Li, J., Sheng, Z., Yao, X., Liu, H., Zhang, X., Yang, Y., Yu, D., Zhang, Y., Xu, Y., Zhang, Z., Huang, T., Liu, W. & Ouyang, H.#, 2020. Classification of four distinct osteoarthritis subtypes with a knee joint tissue transcriptome atlas. Bone Research , 8, 38 link
26. Cinkornpumin, J.K., Kwon, S.Y., Guo, Y. , Hossain, I., Sirois, J., Russett, C.S., Tseng, H., Okae, H., Arima, T., Duchaine, T.F., Liu, W. & Pastor, W.A.#, 2020. Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome. Stem Cell Reports . link
25. Gell, J. J.*, Liu, W. , Sosa, E., Chialastri, A., Hancock, G., Tao, Y., Wamaitha, S. E., Bower, G., Dey, S. S., Clark, A. T.#, 2020. An Extended Culture System that Supports Human Primordial Germ Cell-like Cell Survival and Initiation of DNA Methylation Erasure. Stem Cell Reports , 14(3), 433-446. link

2019

24. Wongpalee, S. P.*, Liu, S.*, Gallego-Bartolomé, J.*, Leitner, A., Aebersold, R., Liu, W. , Yen L., Nohales, M. A., Kuo, P. H., Wohlschlegel J. A., Feng, S., Kay, S. A., Zhou, Z.#, Jacobsen, S. E#, 2019. CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Nature Communications , 10(1), 3916. link
23. Chen, D.*, Sun, N.*, Hou, L.*, Kim, R., Faith, J., Aslanyan, M., Tao Y., Zheng Y., Fu J., Liu W. , Manolis K.#, Clark, A#, 2019. Human Primordial Germ Cells Are Specified from Lineage-Primed Progenitors. Cell Reports ,29(13), 4568-4582.e4565. link
22. Lin, F.*, Meng, X.*, Guo, Y. , Cao, W., Liu, W. , Xia, Q., Hui, Z., Chen, J., Hong, S., Zhang, X., Wu, C., Wang, D., Wang, J., Lu, L., Qian W., Wei, L., Wang, L.#,2019. Epigenetic initiation of the TH17 differentiation program is promoted by Cxxc finger protein 1. Science Advances ,5,eaax1608 link
21. Potok, M.E.*, Wang, Y.*, Xu, L., Zhong, Z., Liu, W. , Feng, S., Naranbaatar, B., Rayatpisheh, S., Wang, Z., Wohlschlegel, J.E., Ausin, I.#, Jacobsen, S.E.#, 2019. Arabidopsis SWR1-associated protein methyl-CpG-binding domain 9 is required for histone H2A. Z deposition. Nature Communications ,10(1), p3352 link
20. Nohales, M.A., Liu, W. , Duffy, T., Nozue, K., Sawa, M., Pruneda-Paz, J.L., Maloof, J.N., Jacobsen, S.E.# and Kay, S.A.#, 2019. Multi-level Modulation of Light Signaling by GIGANTEA Regulates Both the Output and Pace of the Circadian Clock. Developmental Cell , 49(6), pp.840-851. link
19. Gallego-Bartolome, J.*, Liu, W.* , Kuo, P.H., Feng, S., Ghoshal, B., Gardiner, J., Zhao, J.M.C., Park, S.Y., Chory, J. and Jacobsen, S.E.#, 2019. Co-targeting RNA polymerases IV and V promotes efficient de novo DNA methylation in Arabidopsis. Cell , 176(5), pp.1068-1082. link
18. Papikian, A., Liu, W. , Gallego-Bartolomé, J. and Jacobsen, S.E.#, 2019. Site-specific manipulation of Arabidopsis loci using CRISPR-Cas9 SunTag systems. Nature Communications , 10(1), p.729. link
17. Stoddard, C.I., Feng, S., Campbell, M.G., Liu, W. , Wang, H., Zhong, X., Bernatavichute, Y., Cheng, Y., Jacobsen, S.E.# and Narlikar, G.J.#, 2019. A Nucleosome Bridging Mechanism for Activation of a Maintenance DNA Methyltransferase. Molecular Cell , 73(1), pp.73-83. link

2018

16. Chen, D.*, Liu, W.* , Zimmerman, J., Pastor, W.A., Kim, R., Hosohama, L., Ho, J., Aslanyan, M., Gell, J.J., Jacobsen, S.E. and Clark, A.T., 2018. The TFAP2C-Regulated OCT4 Naive Enhancer Is Involved in Human Germline Formation. Cell Reports , 25(13), pp.3591-3602. link
15. Harris, C.J.*, Scheibe, M.*, Wongpalee, S.P., Liu, W. , Cornett, E.M., Vaughan, R.M., Li, X., Chen, W., Xue, Y., Zhong, Z. and Yen, L., 2018. A DNA methylation reader complex that enhances gene transcription. Science , 362(6419), pp.1182-1186. link
14. Pastor, W.A., Liu, W. , Chen, D., Ho, J., Kim, R., Hunt, T.J., Lukianchikov, A., Liu, X., Polo, J.M., Jacobsen, S.E.# and Clark, A.T.#, 2018. TFAP2C regulates transcription in human naive pluripotency by opening enhancers. Nature Cell Biology , 20(5), p.553. link
13. Liu, W.* , Duttke, S.H.*, Hetzel, J., Groth, M., Feng, S., Gallego-Bartolome, J., Zhong, Z., Kuo, H.Y., Wang, Z., Zhai, J., Chory, J., Jacobsen, S.E.#, 2018. RNA-directed DNA methylation involves co-transcriptional small-RNA-guided slicing of polymerase V transcripts in Arabidopsis. Nature Plants , 4(3), p.181. link
12. Gallego-Bartolomé, J.*, Gardiner, J.*, Liu, W.* , Papikian, A.*, Ghoshal, B., Kuo, H.Y., Zhao, J.M.C., Segal, D.J. and Jacobsen, S.E.#, 2018. Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain. Proceedings of the National Academy of Sciences , 115(9), pp.E2125-E2134. link
11. Zhang, Y.*, Harris, C.J.*, Liu, Q.*, Liu, W. , Ausin, I., Long, Y., Xiao, L., Feng, L., Chen, X., Xie, Y., Chen, X., Zhan, L., Feng, S., Li, J.J., Wang, H.#, Zhai, J.#, Jacobsen, S.E.#, 2018. Large-scale comparative epigenomics reveals hierarchical regulation of non-CG methylation in Arabidopsis. Proceedings of the National Academy of Sciences , 115(5), pp.E1069-E1074. link

2017

10. Clark, A.T.#, Gkountela, S., Chen, D., Liu, W. , Sosa, E., Sukhwani, M., Hennebold, J.D. and Orwig, K.E., 2017. Primate primordial germ cells acquire transplantation potential by Carnegie stage 23. Stem Cell Reports , 9(1), pp.329-341. link
9. Chen, D., Liu, W. , Lukianchikov, A., Hancock, G.V., Zimmerman, J., Lowe, M.G., Kim, R., Galic, Z., Irie, N., Surani, M.A., Jacobsen, S.E., Clark, A.T.# 2017. Germline competency of human embryonic stem cells depends on eomesodermin. Biology of Reproduction , 97(6), pp.850-861. link

2016

8. Ausin, I., Feng, S., Yu, C., Liu, W. , Kuo, H.Y., Jacobsen, E.L., Zhai, J., Gallego-Bartolome, J., Wang, L., Egertsdotter, U., Street, N.R., Jacobsen, S.E.#, Wang, H.#, 2016. DNA methylome of the 20-gigabase Norway spruce genome. Proceedings of the National Academy of Sciences , 113(50), pp.E8106-E8113. link
7. Li, S., Yen, L., Pastor, W.A., Johnston, J.B., Du, J., Shew, C.J., Liu, W. , Ho, J., Stender, B., Clark, A.T. and Burlingame, A.L., Daxinger, L.#, Patel, D.J#, Jacobsen, S.E.#, 2016. Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin. Proceedings of the National Academy of Sciences , 113(35), pp.E5108-E5116. link
6. Harris, C.J.*, Husmann, D.*, Liu, W. , El Kasmi, F., Wang, H., Papikian, A., Pastor, W.A., Moissiard, G., Vashisht, A.A., Dangl, J.L., Wohlschlegel, J.A., Jacobsen, S.E.#, 2016. Arabidopsis AtMORC4 and AtMORC7 form nuclear bodies and repress a large number of protein-coding genes. PLoS Genetics , 12(5), p.e1005998. link
5. Pastor, W.A.*, Chen, D.*, Liu, W.* , Kim, R., Sahakyan, A., Lukianchikov, A., Plath, K., Jacobsen, S.E.# and Clark, A.T.#, 2016. Naive human pluripotent cells feature a methylation landscape devoid of blastocyst or germline memory. Cell Stem Cell , 18(3), pp.323-329. link

2015

4. Zhai, J.*, Bischof, S.*, Wang, H., Feng, S., Lee, T.F., Teng, C., Chen, X., Park, S.Y., Liu, L., Gallego-Bartolome, J., Liu, W. , Henderson, I.R., Meyers, B.C., Ausin, I.#, Jacobsen, S.E.#, 2015. A one precursor one siRNA model for Pol IV-dependent siRNA biogenesis. Cell , 163(2), pp.445-455. link

2014

3. Pastor, W.A.*, Stroud, H.*, Nee, K., Liu, W. , Pezic, D., Manakov, S., Lee, S.A., Moissiard, G., Zamudio, N., Bourc’his, D. and Aravin, A.A., Clark, A.T.#, Jacobsen, S.E.#, 2014. MORC1 represses transposable elements in the mouse male germline. Nature Communications , 5, p.5795. link

2013

2. Jiang, Y., Chen, L., Zhang, S., Tong, T., Zhang, W., Liu, W. , Xu, G., Tuan, R.S., Heng, B.C., Crawford, R. and Xiao, Y.,Ouyang, H.W.#, 2013. Incorporation of bioactive polyvinylpyrrolidone–iodine within bilayered collagen scaffolds enhances the differentiation and subchondral osteogenesis of mesenchymal stem cells. Acta Biomaterialia , 9(9), pp.8089-8098. link

2012

1. Zhang, S., Jiang, Y.Z., Zhang, W., Chen, L., Tong, T., Liu, W. , Mu, Q., Liu, H., Ji, J., Ouyang, H.W. and Zou, X.#, 2012. Neonatal desensitization supports long-term survival and functional integration of human embryonic stem cell-derived mesenchymal stem cells in rat joint cartilage without immunosuppression. Stem Cells and Development , 22(1), pp.90-101. link
BIOINFORMATICS

Web tools / Databases

  1. Region Associated DEG START TRYING!

    RAD - Region Associated DEG is a web tool to identify region associated differentially expressed genes.

  2. huARdb

    The Human Antigen Receptor Database.

  3. germlineTE

    The germlineTE single-cell dataset visualizer.

NEWS

What just happened in the lab

2022/6

  • Lab at All-in Cafe.
  • Congratulation to Ziwei Xue, Siqian Jin, and Xinyu Xiang for winning the First prize and third prize of the Student Crossover Innovation Competition in the Campus Poster Day. 恭喜实验室生物信息学专业博士研究生薛子为,相欣雨和科研助理金飔倩同学获得校区学术交叉创新一等奖和三等奖!

2021/12

  • Welcome the joining of our new visiting master student Yiwen Xu. Yiwen is currently the master student in clinical medicine from the The Second Affiliated Hospital, Zhejiang University School of Medicine. 欢迎新成员徐艺文(浙大附属第二医院,硕士研究生)加入实验室!

2021/11

  • Congrats Yixin Guo for winning National scholarship for postgraduate students. 恭喜实验室生物信息学专业博士研究生郭奕鑫获得2021年研究生国家奖学金!

2021/9

  • Welcome the joining of our new Ph.D. Students Lize Wu, Ziwei Xue and our two new master students Ruonan Tian, Xinyi Chen.
  • Congrats Lize Wu et al. for publishing on Nucleic Acid Research. This is a collaboration project with Dr. Lu from ZJE.
  • Congrats Siqian Jin et al., for publishing on Biochemical and Biophysical Research Communications.

2021/8

  • Congrats Wanlu Liu for receiving approval for funding from The General Program of National Natural Science Foundation of China
  • Congrats Wanlu Liu for publishing on Stem Cell Research. This is a collaboration project with Dr. Amander T. Clark from UCLA, USA.

2021/7

  • Congrats Wanlu Liu for receiving Justice, Equity, Diversity and Inclusion (JEDI) awards from the Life Science Editors Foundation (LSEF). For more information, please visit http://lifescienceeditors.org/

2021/5

  • Lab hike to Jing Mountain in Hangzhou. We enjoy the outdoors.
OUTSIDEOFSCIENCE

Wow.

CONTACT US

Get In Touch

Mailing Address

A314, ZJU-UoE Institute,
718 East Haizhou Rd., Haining, Zhejiang 314400, P.R. China
email: wanluliu@intl.zju.edu.cn

通讯地址

A314, 浙江大学爱丁堡大学联合学院
浙江省海宁市海州东路 718 号,邮编:314400
电子邮箱:wanluliu@intl.zju.edu.cn

Thanks for your interest in LabW 😎

We are alwasys looking for motivated and creative researchers specialized in Molecular Biology, Cellular Biology, Bioinformatics, Computer Science, Statistics and Engineering to join us.

If you are interested in being part of the Lab W, please send your CV and a short research interests to wanluliu@intl.zju.edu.cn

Positions available are : postdocs, graduate students, research assistants , undergraduate research interns.


感谢您对我们实验室的兴趣,我们实验室长期欢迎不同背景包括分子生物学、细胞生物学、生物信息学、计算机科学、统计学、和工科背景的博士后、研究生、科研助理、本科生加入我们。如果你对加入我们感兴趣,欢迎您发送一份简历(CV)以及一段简短的研究兴趣到wanluliu@intl.zju.edu.cn

Wanlu Liu

Wanlu Liu is an Assistant Professor in the ZJE institute at Zhejiang University. She is a former postdoctoral researcher in the department of Molecular Cellular and Developmental Biology at the University of California, Los Angeles, where she received a Ph.D. in molecular biology from the Molecular Biology Institute. She is passionate about building bioinformatics tools, mining big genomics data, and uncovering epigenetic mechanisms. She enjoys painting, photography, and playing badminton. She dreams of one day going pro in photography.

刘琬璐,浙江大学爱丁堡大学联合学院助理教授、研究员、博士生导师。本科毕业于浙江大学基础医学国家理科基地班,取得医学学士学位。博士毕业于美国加州大学洛杉矶分校。研究兴趣为:构建生物信息学分析工具、挖掘基因组学大数据以及探索表观遗传调控机制。在学术与教学以外,她还喜欢画画、摄影以及羽毛球。曾在某游戏中连抽600张神秘符咒不出SSR从而达成”非洲大阴阳师“称号。

个人主页: https://person.zju.edu.cn/labw

Siqian Jin

Siqian Jin is a lab manager at Zhejiang University, ZJU-UoE institute. She gained a M.S. (Ophthalmology) from School of Ophthalmology & Optometry, Wenzhou Mecdical University. Three years'research training in Laboratory for Stem Cell & Retinal Regeneration let her specialize in stem cell related experiments. She has a wide range of hobbies, especially Chinese chess, woodworking, Kendo, and running.

金飔倩,浙江大学爱丁堡大学联合学院科研助理。本科毕业于山东大学临床医学院临床医学专业。硕士毕业于温州医科大学眼视光学院、生物医学工程学院眼科学专业。她擅长干细胞相关实验,尤其是胚胎干细胞。她业余爱好广泛,比较喜欢中国象棋,木工手工,剑道,长跑,另外还很喜欢吃各种小吃美食。

Junxin Lin

Junxin Lin is currently a postdoctoral research associate at Zhejiang University, ZJU-UoE institute. His research interests is using bioinformatics, molecular and cellular approaches to study the development/diseases of musculoskeletal system and biology of mesenchymal stem cells. His findings has been published in journals including Bone Research, Advanced Science, the American Journal of Sports Medicine and so on. He likes swimming and cooking in his spare time.

林俊鑫,浙江大学爱丁堡大学联合学院博士后、助理研究员。本科毕业于浙江大学动物科学学院动物医学专业,获农学学士学位。博士毕业于浙江大学医学院干细胞和再生医学专业。研究兴趣为:利用生物信息学、分子生物学和细胞生物学等多学科交叉手段研究间充质干细胞的分化命运调控以及肌肉骨骼系统发育过程和异位骨化等病理机制。空闲时间,他喜欢游泳和做饭。

Yixin Guo

Yixin Guo is a PhD student majoring in bioinformatics at ZJE institution of Zhejiang University. He obtained an engineering bachelor' degree from Department of Life Science and Engineering in Southwest Jiaotong University. His studies dig into multi-omics data integration analysis, genomic big data mining and analysis as well as bioinformatics analysis tool development. As for hobbies, Mr.Guo is interested and talented in various sports, including tennis, badminton, table tennis, and billiards.

郭奕鑫,浙江大学爱丁堡大学联合学院生物信息学博士生。本科毕业于西南交通大学生命科学与工程学院,取得工学学士学位。研究方向为:多组学数据整合分析、生物信息学分析工具开发、基因组大数据挖掘分析。在业余生活方面,他擅长多种球类运动,比如网球、羽毛球、乒乓球、桌球等。

Dengfeng Ruan

Dengfeng Ruan is a PhD student majoring in orthopedics at Zhejiang University School of Medicine. He obtained a M.S. in Surgery and recived standardized residency training in The Second Affiliated Hospital, Zhejiang University School of Medicine. And he now receives scientific research training in Lab W. His research intersects include development/regeneration of musculoskeletal system and biology of mesenchymal stem cells. He enjoys traveling and experiencing various cultures, sights and lives. He also had a wide-range interests in cooking, reading, handicraft and so on.

阮登峰,浙江大学医学院外科学(骨科)博士生。本科毕业于温州医科大学临床医学专业,硕士毕业于浙江大学医学院外科学专业,并于浙江大学医学院附属第二医院完成住院医师规范化培训。目前他在实验室接受联合培养,研究方向为运动系统的发育与再生以及间充质干细胞的分化命运调控。他的业余爱好广泛,对做饭、手工、羽毛球、乒乓球等都有兴趣,另外他喜欢旅行去见各种新的风景。

Xinyu Xiang

Xinyu Xiang is a PhD student majoring in bioinformatics at ZJE institution of Zhejiang University. She obtained an Applied Bioscience' Degree from College of Agriculture and Biotechnology in Zhejiang University. By making use of multi-omics data integration analysis as well as stem cell cultivation and induction techniques, she is exploring the mechanism of stem cell and early embryo development. Ms.Xiang has a wide range of interests, she likes experience local culture while traveling and tries to be an avid gym goer.

相欣雨,浙江大学爱丁堡大学联合学院生物信息学博士生。本科毕业于浙江大学农业与生物技术学院。她的研究方向是:利用多组学数据整合分析与挖掘和干细胞培养与诱导技术探索干细胞与早期胚胎发育调控机制。她喜欢说走就走的旅行,同时也是健身房养老型选手。

Bing Gao

Bing Gao is a Master Student of bioinformatics at Zhejiang University. He graduated from Beijing University of Chemical Technology and majored in Bioengineering. He currently engaged in protein purification in the laboratory. He loves sports, fitness + various ball sports, especially running and trail, and often participates in marathon and trail running events.

高兵是浙江大学生物信息学专业的硕士生,本科毕业于北京化工大学生物工程专业,目前在实验室从事蛋白纯化工作。他热爱运动,健身 + 各种球类运动,尤其喜欢跑步和Trail,经常参加马拉松赛事和越野跑赛事。

Ziwei Xue

Ziwei Xue is a PhD student major in bioinformatics at ZJE institution of Zhejiang University. My research interests include: Developing bioinformatic applications to analyze multi-omics data. I love exploring unknown in the field of bioinformatics, and I also enjoy designing graphics and websites. Coding is my both professional and amateurish habit. I am quite an Otaku so try not bother me when I am not busy (unless...)

我是浙江大学浙江大学生物信息学专业的博士生。研究兴趣为:通过生物信息学的手段,开发相关的程式/算法解决多组学分析的问题。我喜欢探索生物信息学领域的未知事物,也喜欢平面设计和构建好看的网站。Coding是我专业和业余的爱好。是个现充,所以在我不忙的时候不要打扰我(除非是帅哥美女)。🏸🎾可约。

个人主页: https://beiusxzw.github.io

Lize Wu

Lize Wu is a PhD student majoring in immunology and bioinformatics at Zhejiang University School of Medicine. He obtained the bachelor degree in biomedical science from Zhejiang University. His research interests are developing bioinformatic tools to analyze immunology-related data and revealing immunological mechanism by both dry- and wet-lab approaches. Lize is facinated with travelling and flying.

吴利则,浙江大学医学院免疫学与生物信息学交叉培养博士生,本科毕业于浙江大学并获得生物医学学士学位。利则的研究兴趣是开发生物信息学工具用以挖掘分析免疫学相关数据,以及使用湿实验和干实验的手段研究免疫学机制。生活上,利则十分着迷于旅行以及和飞行有关的事情。

Xinyi Chen

Xinyi Chen is a Master Student of bioinformatics in the ZJE institute at Zhejiang University. She graduated from College of Agriculture and Biotechnology, Zhejiang University. Her research interests are using bioinformatics, molecular and cellular approaches to study the development/diseases of musculoskeletal system. She is a person who loves life and likes traveling and photography in her spare time. Traveling around the world is her biggest dream.

陈心怡,浙江大学爱丁堡大学联合学院生物信息学专业硕士生。本科毕业于浙江大学农业与生物技术学院。研究兴趣为:利用生物信息学、分子生物学和细胞生物学等多学科交叉手段研究间充质干细胞的分化命运调控。她是个热爱生活的人,空闲时间喜欢旅游和摄影,环游世界是她最大的梦想。

Ruonan Tian

Ruonan Tian is a Master Student of bioinformatics in the ZJE institute at Zhejiang University. She graduated from Huazhong Agricultural University, majoring in bioinformatics. For her, learning or trying something new is an enjoyable thing. Doing research and exploring new research fileds are also what she enjoys . She loves various sports, such as badminton, basketball and so on. Besides, she is a fangirl who changes idols frequently.

田若楠,浙江大学爱丁堡大学联合学院生物信息学专业硕士生,本科毕业于华中农业大学信息学院生物信息学专业。对于她来说,尝试新东西是一件很快乐的事情,因此她也喜欢做研究。她喜欢各种运动,比如羽毛球、篮球、跑步等,同时她还是一个换墙头非常频繁的追星女孩,漂亮的小姐姐和小哥哥令她感到愉悦。

3. 个人主页: https://ruonantian.github.io/rolan/

Yiwen Xu

Chao Dai

Jinchun Zhang

Yaqi Su

Ruihong Yuan

Zhejian Yu

Xinyue Huang